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Assignment of Borrelia burgdorferi strains G25 and VS461 to the Borrelia garinii and Borrelia afzelii genospecies, respectively: a comparison of OspA protein sequences.

par Godfroid, Edmond ;Ben Messaoud, Abdelouahid ;Poliszczak, A.;Lobet, Y.;Bollen, Alex
Référence DNA sequence : the journal of DNA sequencing and mapping, 5, 4, page (251-254)
Publication Publié, 1995

Article révisé par les pairs

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Résumé :

The nucleotide sequence encoding the Outer Surface Protein A (OspA) from two Borrelia burgdorferi sensu lato isolates, G25 and VS461, has been determined. On the basis of a phylogenetic analysis, strains G25 and VS461 were respectively assigned to the B. garinii and B. afzelii genospecies. Comparative analysis of OspA proteins from 26 different B. burgdorferi sensu lato strains involved in Lyme disease indicated a higher heterogeneity in the B. garinii genospecies than in the two other genospecies, B. burgdorferi sensu stricto and B. afzelii.