Résumé : The presence of emerging organic pollutants is a growing concern in terms of water quality. Bioremediation, particularly the use of white rot fungi, is a promising advanced treatment technique. The present study takes a multiscale approach. It considers both the trickle-bed reactor as a whole and the flow on a single carrier in idealised conditions. This allows us to evaluate the wettability of the reactor, as well as the impact of flow conditions on the mycelial growth structure and the resulting limitation of mass transfer. Mycelium was inoculated onto a 30 x 8 mm wooden dowel using the basidiomycete Coriolopsis gallica 1184 strain. The trickle-bed reactor had a treatment volume of 4 L, with continuous flow at 5 mL/min. The inoculated dowel was then placed in a system with controlled low-flow falling film and full wetting. Remazol Brilliant Blue R degradation and phase proportions were measured at different growth stages. Biomass production, lignin-modifying enzyme activity and oxygen microprofiles were also determined in order to characterise the thickness of the biofilm and the structure of the liquid film. Continuous degradation of 30% was achieved on the reactor scale. The liquid phase accounted for 3.33% of the total volume, while the solid phase accounted for 49%. These results were compared with those of previous experiments involving Trametes versicolor under identical conditions, which exhibited significantly lower degradation performance. These differences were attributed to variations in the mycelial structure, emphasising the importance of structure in relation to the system's overall treatment capacity.