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ider(9)(q10)t(9;22)(q34;q11) is a recurrent chromosomal abnormality in acute lymphoblastic leukemia and lymphatic blastic phase of chronic myelogenous leukemia.

par Dierlamm, Judith;Michaux, Lucienne;Kröger, N;Wlodarska, Iwona;Martiat, Philippe ;Zeller, W;Seeger, D;Mecucci, C;Van den Berghe, Herman;Hossfeld, D K
Référence Cancer genetics and cytogenetics, 89, 2, page (109-113)
Publication Publié, 1996-07

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Résumé :

We report on two cases, one with acute lymphoblastic leukemia and a second with lymphatic blastic phase of Philadelphia chromosome-positive chronic myelogenous leukemia, cytogenetically characterized by ider(9)(q10)t(9;22)(q34;q11). Our findings and the data of the 4 cases previously published indicate that ider(9)(q10)t(9;22)(q34;q11) represents a rare but recurrent chromosomal abnormality occurring in hematological malignancies with lymphoid differentiation, namely acute lymphoblastic leukemia and lymphatic blastic phase of chronic myelogenous leukemia, and most likely evolves from a preexistent der(9) involved in the standard t(9;22).