par Boeynaems, Jean-Marie ;Cantraine, Francis
Référence Analytical biochemistry, 91, 1, page (32-45)
Publication Publié, 1978-11
Article révisé par les pairs
Résumé : The calculation of the first four moments of saturation functions is proposed as a method to describe the properties of enzymes or receptors models. The values of these moments in the case of the Langmuir or Michaelis-Menten equation and the Hill equation are reviewed. They have been calculated for the second degree Adair equation and in the case of binding site heterogeneity. A method for generalization to cases of greater complexity is also proposed. The advantage of this method over the classical ones--graphical representations and derivation of coefficients like nH, [L]0.9/[L]0.1 ...--is essentially that the moments are defined by one single value independently of any particular model for the whole of the saturation curve.