par Hobbi, Parinaz 
Président du jury Debaste, Frédéric
Promoteur Shavandi, Armin
Publication Non publié, 2024-09-23
Président du jury Debaste, Frédéric
Promoteur Shavandi, Armin
Publication Non publié, 2024-09-23
Thèse de doctorat
| Résumé : | The research performed in this thesis investigated the extraction and characterization of bioactive polyphenols from food industry apple waste that can have potential in biomedical applications. The findings of this research highlighted the importance of the valorization of apple waste for the extraction of bioactive polyphenolic compounds that can be utilized for the fabrication of polyphenol-functionalized scaffolds with potential in bone tissue engineering. The results of this research showed that the utilization of phloridzin as a main polyphenol of apple waste could provide promising potential in enhancing the morphological, mechanical, and biological characteristics of the scaffolds, thereby demonstrating the potential for bone tissue regeneration. It was found that polyphenolic compounds recovered from waste cannot only help mitigate the environmental pollution caused by huge amounts of waste disposed of in landfills but also be effectively employed for the functionalization of biomaterial that can be utilized in biomedical applications. Moreover, the kinetic information provided in this research can be helpful for future large-scale designing and process control to improve the economy and reduce the scaling-up cost for the valorization of apple waste. |
