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HTLV-I infection of WE17/10 CD4(+) cell line leads to progressive alteration of Ca(2+) influx that eventually results in loss of CD7 expression and activation of an antiapoptotic pathway involving AKT and BAD wich paves the way for malignant transformation

par Akl, Haidar ;Badran, Bassam ;Zein, N. E.;Bex, Françoise ;Sotiriou, Christos ;Willard-Gallo, Karen ;Burny, Arsène ;Martiat, Philippe
Référence Leukemia, 21, page (788-796)
Publication Publié, 2007-02-08

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Titre:	HTLV-I infection of WE17/10 CD4(+) cell line leads to progressive alteration of Ca(2+) influx that eventually results in loss of CD7 expression and activation of an antiapoptotic pathway involving AKT and BAD wich paves the way for malignant transformation
Auteur:	Akl, Haidar; Badran, Bassam; Zein, N. E.; Bex, Françoise; Sotiriou, Christos; Willard-Gallo, Karen; Burny, Arsène; Martiat, Philippe
Informations sur la publication:	Leukemia, 21, page (788-796)
Statut de publication:	Publié, 2007-02-08
Sujet CREF:	Cancérologie
MeSH keywords:	Antigens, CD7 -- genetics
	Antigens, CD7 -- physiology
	Apoptosis
	CD4-Positive T-Lymphocytes -- drug effects
	CD4-Positive T-Lymphocytes -- immunology
	CD4-Positive T-Lymphocytes -- pathology
	Calcium Signaling -- physiology
	Cell Line
	Cell Transformation, Neoplastic
	Flow Cytometry
	Gene Expression Regulation, Viral
	HTLV-I Infections -- physiopathology
	Humans
	Ionomycin -- pharmacology
	Oncogene Protein v-akt -- genetics
	Oncogene Protein v-akt -- physiology
	RNA -- genetics
	RNA -- isolation & purification
	Reverse Transcriptase Polymerase Chain Reaction
	bcl-Associated Death Protein -- genetics
	bcl-Associated Death Protein -- physiology
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
	SCOPUS: ar.j
Langue:	Anglais
Identificateurs:	urn:issn:0887-6924
	info:doi/10.1038/sj.leu.2404585
	info:pii/2404585
	info:scp/33947415379
	info:pmid/17287851
	ha-0001