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The role of the 21-gene assay in the neoadjuvant setting for hormone receptor-positive HER2-negative breast cancer: Impact on systemic and surgical treatment decisions

par Zotano, Guerrero;Allweis, Tanir T.M.;Foerster, Robert;Palmieri, Carlo;Gluz, Oleg;Chia, Stephen;Sotiriou, Christos ;Bianchini, Giampaolo
Référence Cancer treatment reviews, 147, 103161
Publication Publié, 2026-06

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Titre:	The role of the 21-gene assay in the neoadjuvant setting for hormone receptor-positive HER2-negative breast cancer: Impact on systemic and surgical treatment decisions
Auteur:	Zotano, Guerrero; Allweis, Tanir T.M.; Foerster, Robert; Palmieri, Carlo; Gluz, Oleg; Chia, Stephen; Sotiriou, Christos; Bianchini, Giampaolo
Informations sur la publication:	Cancer treatment reviews, 147, 103161
Statut de publication:	Publié, 2026-06
Sujet CREF:	Imagerie médicale, radiologie, tomographie
	Cancérologie
Mots-clés:	21-gene assay
	Breast cancer
	Core biopsy
	Multigene assay
	Neoadjuvant therapy
	Oncotype DX
	Prognosis
	Recurrence Score
MeSH keywords:	Humans
	Breast Neoplasms -- genetics -- drug therapy -- pathology -- surgery -- therapy -- metabolism
	Female
	Neoadjuvant Therapy -- methods
	Erb-b2 Receptor Tyrosine Kinases -- metabolism
	Receptors, Estrogen -- metabolism
	Receptors, Progesterone -- metabolism
	Neoplasm Recurrence, Local -- genetics
	Prognosis
	Gene Expression Profiling -- methods
Note générale:	SCOPUS: ar.j
Langue:	Anglais
Identificateurs:	urn:issn:0305-7372
	info:doi/10.1016/j.ctrv.2026.103161
	info:pii/S0305737226000757
	info:scp/105040558410
	info:pmid/42218834