Résumé : Since the beginning of the COVID-19 pandemic, a catastrophic scenario in terms of mortality was predicted in Sub-Saharan Africa. In this correspondence, we have compared adjusted case fatality rate of Belgian to that of Cameroon. Our estimates showed that, even with the Belgian scenario, about 2319 COVID-19 deaths should be expected in Cameroon, i.e. 10.3 times lower per inhabitant mortality. In conclusion, the youthfulness of the Cameroonian population could be the main factor of low mortality rate related to COVID-19 in this country. However, studies are needed to eliminate other factors, notably genetic and environmental.