par Shakeri, Hadis 
;Gevaert, Andreas B;Schrijvers, Dorien M;De Meyer, Guido R Y;De Keulenaer, Gilles W;Guns, Pieter-Jan D F;Lemmens, Katrien;Segers, Vincent F M
Référence Cardiovascular Research, 114, 7, page (1041-1051)
Publication Publié, 2018-12-01
;Gevaert, Andreas B;Schrijvers, Dorien M;De Meyer, Guido R Y;De Keulenaer, Gilles W;Guns, Pieter-Jan D F;Lemmens, Katrien;Segers, Vincent F MRéférence Cardiovascular Research, 114, 7, page (1041-1051)
Publication Publié, 2018-12-01
Article révisé par les pairs
| Résumé : | Cardiovascular ageing is a key determinant of life expectancy. Cellular senescence, a state of irreversible cell cycle arrest, is an important contributor to ageing due to the accumulation of damaged cells. Targeting cellular senescence could prevent age-related cardiovascular diseases. In this study, we investigated the effects of neuregulin-1 (NRG-1), an epidermal growth factor with cardioprotective and anti-atherosclerotic effects, on cellular senescence. |
