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A novel chalcone derivative which acts as a microtubule depolymerising agent and an inhibitor of P-gp and BCRP in in-vitro and in-vivo glioblastoma models.

par Boumendjel, Ahcène;McLeer-Florin, Anne;Champelovier, Pierre;Allegro, Diane;Muhammad, Dima;Souard, Florence ;Derouazi, Madiha;Peyrot, Vincent;Toussaint, Bertrand;Boutonnat, Jean
Référence BMC cancer, 9, page (242)
Publication Publié, 2009-07

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Titre:	A novel chalcone derivative which acts as a microtubule depolymerising agent and an inhibitor of P-gp and BCRP in in-vitro and in-vivo glioblastoma models.
Auteur:	Boumendjel, Ahcène; McLeer-Florin, Anne; Champelovier, Pierre; Allegro, Diane; Muhammad, Dima; Souard, Florence; Derouazi, Madiha; Peyrot, Vincent; Toussaint, Bertrand; Boutonnat, Jean
Informations sur la publication:	BMC cancer, 9, page (242)
Statut de publication:	Publié, 2009-07
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	ATP Binding Cassette Transporter, Subfamily B, Member 1 -- antagonists & inhibitors -- metabolism
	Animals
	Antineoplastic Agents -- pharmacology
	Apoptosis
	Blood-Brain Barrier
	Brain Neoplasms -- metabolism
	Cell Line, Tumor
	Chalcone -- analogs & derivatives
	Chalcones -- pharmacology
	Glioblastoma -- metabolism
	Humans
	Mice
	Mice, Inbred C57BL
	Microtubules -- metabolism
	Proto-Oncogene Proteins c-bcr -- antagonists & inhibitors -- metabolism
	Rats
Langue:	Anglais
Identificateurs:	urn:issn:1471-2407
	info:doi/10.1186/1471-2407-9-242
	info:pii/1471-2407-9-242
	info:pmid/19619277
	PMC2717121