Titre:
  • Optimization of Experimental Parameters to Explore Small-Ligand/Aptamer Interactions through Use of (1) H NMR Spectroscopy and Molecular Modeling.
Auteur:Souard, Florence; Perrier, Sandrine; Noël, Vincent; Fave, Claire; Fiore, Emmanuelle; Peyrin, Eric; Garcia, Julian; Vanhaverbeke, Cécile
Informations sur la publication:Chemistry, 21, 44, page (15740-15748)
Statut de publication:Publié, 2015-10
Sujet CREF:Sciences bio-médicales et agricoles
Mots-clés:NMR spectroscopy
TR-NOESY
aptamers
design of experiments
structure elucidation
MeSH keywords:Adenosine Monophosphate -- chemistry
Aptamers, Nucleotide -- chemistry -- metabolism
Binding Sites
Ligands
Magnetic Resonance Spectroscopy
Molecular Dynamics Simulation
Nucleic Acid Conformation
Tyrosine -- analogs & derivatives -- chemistry
Langue:Anglais
Identificateurs:urn:issn:0947-6539
info:doi/10.1002/chem.201501527
info:pmid/26356596