par Najar, Mehdi ;Fayyad Kazan, Hussein ;Faour, Wissam H;El Taghdouini, Adil;Raicevic, Gordana ;Najimi, Mustapha;Toungouz Nevessignsky, Michel ;van Grunsven, Leo A;Sokal, Etienne M;Lagneaux, Laurence
Référence Cytokine, 90, page (130-134)
Publication Publié, 2016-11
Référence Cytokine, 90, page (130-134)
Publication Publié, 2016-11
Article révisé par les pairs
Résumé : | Uncertainty about the safety of cell therapy continues to be a major challenge to the medical community. Inflammation and the associated immune response represent a major safety concern hampering the development of long-term clinical therapy. In vivo interactions between the cell graft and the host immune system are mediated by functional environmental sensors and stressors that play significant roles in the immunobiology of the graft. Within this context, human liver stellate cells (HSC) demonstrated marked immunological plasticity that has main importance for future liver cell therapy application. |