Résumé : Clinical and hemodynamic studies of 7 cases of patent ductus arteriosus gave us the following results: (1) The pulmonary blood pressures are generally normal in cases of patent ductus arteriosus. (2) However, some patients presenting a patent ductus arteriosus may have a very marked pulmonary hypertension: this hypertension does not depend on the shunt and is very probably primary; it might result from a state of constriction in Ihe small pulmonary vessels; this hypertension provokes in Ihe end irreversible vascular alterations. (3) Patients with a patent ductus arteriosus associated with a pulmonary hypertension present a particular clinical picture: the diastolic component of their murmur is absent; cardiopathy is badly tolerated by them; during an exercise test, they present a deficiency in oxygen of their arterial blood and a decrease of the ratio ot oxygen consumed per liter of ventilation; in some cases there may be cyanosis and clubbing. (4) There is no electrocardiographic pattern characteristic ot the patent ductus arteriosus; very different aspects can be observed. In opposition to common opinions, tracings with a right axis deviation are no exception. Anyway, there is no constant relation between the importance of the shunt and the electric axis deviation. © 1952 S. Karger AG, Basel.