par De Graef, Jacques 
;Woussen Colle, Marie-Claire ;Willems, Glenda
Référence Acta gastro-enterologica Belgica (Ed. multilingue), 39, 7-8, page (225-235)
Publication Publié, 1976
;Woussen Colle, Marie-Claire ;Willems, Glenda Référence Acta gastro-enterologica Belgica (Ed. multilingue), 39, 7-8, page (225-235)
Publication Publié, 1976
Article révisé par les pairs
| Résumé : | A test meal was given to 29 patients. Some presented a peptic ulcer, a gastric cancer or a recurrent ulceration after previous vagotomy or gastrectomy. Basal and post feeding gastrinemia were determined by radioimmunoassay. Two duodenal ulcer patients, one of whom had been previously vagotomized, exhibited a marked postprandial hypergastrinemia suggesting the presence of an antral G cell hyperplasia. The variation in the gastrin response to a standard meal in a given subject remains within acceptable limits, and such a test may thus be used to estimate the endocrine function of the antrum in man. This test is useful in surgical patients to detect the presence of an antral endocrine hyperactivity and thus to select the proper surgical procedure to be used to cure the peptic ulcer disease. Wide variations of the basal and stimulated gastrinemia were observed in the group of healthy volunteers and in the groups of patients with gastric diseases. The estimation of the gastrinemia is thus not useful in medical patients with gastric diseases, unless the presence of a gastric atrophy or of a Zollinger Ellison syndrome is suspected. |
