par Yserbyt, Jonas;Dooms, Christophe;Ninane, Vincent ;Alamé, Touffic
Référence Journal of Bronchology & Interventional Pulmonology, 20, 2, page (159-163)
Publication Publié, 2013-04
Article révisé par les pairs
Résumé : Pulmonary alveolar microlithiasis (PAM) is a rare disease in which calcium-phosphate microliths accumulate within the alveolar space. We report cases of 2 siblings with PAM, presenting differently as regards the distribution and clinical severity. Immune cytologic analysis of bronchoalveolar lavage showed a CD4+ alveolitis in the radiologically most affected patient, whereas the least affected had a normal bronchoalveolar lavage analysis, demonstrating the low specificity of immune cytologic lavage analysis in diagnosing familial PAM. For the first time, we describe the endoscopic findings using a probe-based confocal laser endomicroscopy. © 2013 Lippincott Williams & Wilkins.