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ETUDE AUTORADIOGRAPHIQUE DE L'INCORPORATION DE LA PROLINE DANS LES PROTEINES CEREBRALES. INFLUENCE DE L'APPRENTISSAGE ET DE L'ADMINISTRATION D'ASPARAGINASE

par Peters, Elisabeth
Référence Acta neurologica belgica, 75, 3-4, page (143-150)
Publication Publié, 1975

Article révisé par les pairs

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Résumé :

The distribution of labelled proteins in the brain after the injection of tritiated proline into the third ventricle was studied by autoradiography. In discrete areas, the incorporation proceeds at a faster rate after an avoidance training. The difference between trained and resting animals is much more evident after the injection of 100 units of L asparaginase. It is suggested that L asparaginase impairs longterm memory through the inhibition of protein synthesis.