par Robberecht, Patrick 
;De Neef, Philippe ;Vandermeeren, Alain ;Vandermeers-Piret, Marie-Claire ;Svoboda, Michal ;Meuris, Sylvain ;De Graef, Jacques ;Woussen Colle, Marie-Claire ;Yanaihara, C.;Yanaihara, N.;Christophe, Jean
Référence FEBS letters, 190, 1, page (142-146)
Publication Publié, 1985
;De Neef, Philippe ;Vandermeeren, Alain ;Vandermeers-Piret, Marie-Claire ;Svoboda, Michal ;Meuris, Sylvain ;De Graef, Jacques ;Woussen Colle, Marie-Claire ;Yanaihara, C.;Yanaihara, N.;Christophe, Jean Référence FEBS letters, 190, 1, page (142-146)
Publication Publié, 1985
Article révisé par les pairs
| Résumé : | Helodermin is a biologically active peptide isolated from the venom of the Gila monster lizard (Heloderma suspectum) whose structure is related to that of vasoactive intestinal peptide and secretin. Using a specific radioimmunoassay based on antisera prepared by immunizing rabbits with natural helodermin, we demonstrated the presence of helodermin-like material in mammalian salivary glands, including parotid, submaxillary and sublingual glands from rat and dog, and parotid and submaxillary glands from man. All helodermin-like materials had an apparent molecular mass of 4-12 kDa. Dog saliva, collected after pilocarpine stimulation, revealed similar immunoreactivity with a major component around 6 kDa. |
