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Ritodrine-induced acidosis in pregnancy

par Désir, Daniel ;Van Coevorden, Anne ;Kirkpatrick, Christine ;Caufriez, Anne
Référence British medical journal, 2, 6146, page (1194)
Publication Publié, 1978

Article révisé par les pairs

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Résumé :

Beta-sympathomimetic agents such as salbutamol, terbutaline, and ritodrine are commonly used to prevent premature delivery but may have metabolic side effects, particularly in the case of salbutamol. Enhanced lipolysis and glycolysis result in raised blood glucose, fatty acid, and lactate concentrations and a fall in serum bicarbonate. Severe metabolic acidosis, however, has been described only in pregnancy complicated by diabetes. A case of decompensated acidosis that occurred during an infusion of ritodrine is reported.