Titre:
  • In vitro anticancer activity, toxicity and structure-activity relationships of phyllostictine A, a natural oxazatricycloalkenone produced by the fungus Phyllosticta cirsii.
Auteur:Le Calve, Benjamin; Lallemand, Benjamin; Perrone, Carmen; Lenglet, Gaëlle; Depauw, Sabine; Van Goietsenoven, Gwendoline; Bury, Marina; Vurro, Maurizio; Herphelin, Françoise; Andolfi, Anna; Zonno, Maria Chiara; Mathieu, Véronique; Dufrasne, François; Van Antwerpen, Pierre; Poumay, Yves; David-Cordonnier, Marie-Hélène; Evidente, Antonio; Kiss, Robert
Informations sur la publication:Toxicology and applied pharmacology, 254, 1, page (8-17)
Statut de publication:Publié, 2011-07
Sujet CREF:Sciences bio-médicales et agricoles
Mots-clés:Apoptosis
Cancer cells
Cell death
Cell proliferation
Chemical stability
Hemisyntheses
In vitro
Normal cells
Phyllostictines
Videomicroscopy
MeSH keywords:Alkylation -- drug effects
Animals
Antibiotics, Antineoplastic -- pharmacology -- toxicity
Apoptosis -- drug effects
Ascomycota -- metabolism
Cell Cycle -- drug effects
Cell Line
Cell Line, Tumor
DNA -- metabolism
Glutathione -- metabolism
Heterocyclic Compounds, 3-Ring -- pharmacology -- toxicity
Humans
Microscopy, Video
Neoplasms -- drug therapy
Structure-Activity Relationship
Note générale:Journal Article
Research Support, Non-U.S. Gov't
SCOPUS: ar.j
Langue:Anglais
Identificateurs:urn:issn:0041-008X
info:doi/10.1016/j.taap.2011.03.027
info:pii/S0041-008X(11)00131-1
info:scp/79958006806
info:pmid/21504755