par Deleers, Michel 
;Gelbcke, Michel ;Malaisse, Willy
Référence Proceedings of the National Academy of Sciences of the United States of America, 78, 1, page (279-282)
Publication Publié, 1981-01
;Gelbcke, Michel ;Malaisse, Willy Référence Proceedings of the National Academy of Sciences of the United States of America, 78, 1, page (279-282)
Publication Publié, 1981-01
Article révisé par les pairs
| Résumé : | The ionophores A23187 and bromolasalocid (Br-X537A) acted synergistically in translocating Ca(2+) from an aqueous into an organic immiscible phase or in mediating Ca(2+) transport across the organic phase, the effects obtained in the simultaneous presence of both ionophores being greater than those expected from a summation of the individual effects of each ionophore. The nuclear magnetic resonance spectrum obtained when the complexation of Ca(2+) occurred in the presence of both ionophores differed strikingly from the individual spectra obtained with the A23187-Ca and Br-X537A-Ca complexes. These findings indicate that the two ionophores are able to form hybrid complexes with Ca(2+). |
