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Di- and tri-organotin derivatives of 3S,4S-3-[(R)-1-tert-butyl-dimethylsilyloxy)ethyl]-4-[(r)-1-carboxyethyl)-2-azetidinone: synthesis, characterization and in vitro antitumour activity

par Gielen, Marcel ;Dalil, Hassan ;Biesemans, Monique;Mahieu, Bernard;De Vos, Danièle ;Willem, Rudolph
Référence Applied organometallic chemistry, 13, 7, page (515-520)
Publication Publié, 1999-07

Article révisé par les pairs

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Résumé :

Di-n-butyl-, triphenyl and tri-n-butyltin derivatives of 3S,4S-3-[(R)-1-(tert-butyldimethyl-­silyloxy)ethyl-4-[(R)-1-carboxyethyl]-2-azetidi-­none were synthesized and characterized. Their antitumour activity was screened against seven tumoural cell lines of human origin. Copyright © 1999 John Wiley & Sons, Ltd.