par Gielen, Marcel ;El Khloufi, A;Biesemans, Monique;Bouhdid, Abdeslam;De Vos, Danièle ;Mahieu, Bernard;Willem, Rudolph
Référence Metal-based drugs, 1, 4, page (305-309)
Publication Publié, 1994
Référence Metal-based drugs, 1, 4, page (305-309)
Publication Publié, 1994
Article révisé par les pairs
Résumé : | The synthesis and spectral characterization of six novel triphenyltin compounds are described. The in vitro antitumour activity of three of these compounds against two human tumour cell lines, MCF-7, a mammary tumour, and WiDr, a colon carcinoma, was determined. All three compounds are more active than cis-platin, etoposide and doxorubicin against both tumour cell lines. They are as active as mitomycin C against WiDr, but less active against MCF-7. |