par Gielen, Marcel ;Handlir, K;Hollein, M;De Vos, Danièle
Référence Metal-based drugs, 7, 5, page (233-236)
Publication Publié, 2000
Référence Metal-based drugs, 7, 5, page (233-236)
Publication Publié, 2000
Article révisé par les pairs
Résumé : | The synthesis and characterization of four di- and tri-n-butyltin cysteaminates and N,N-dimethylcysteaminates and three protonated / quaternized derivatives are reported. They all exhibit moderate or high in vitro cytotoxic activity. Six of seven compounds presented in this work are more active than cisplatin, etoposide and 5-fluorouracil, but less active than methotrexate and doxorubicin. |