par Lossignol, Dominique ;Obiols-Portis, Myriam;Body, Jean-Jacques
Référence Supportive care in cancer, 13, 3, page (188-193)
Publication Publié, 2005-03
Article révisé par les pairs
Résumé : GOALS AND WORK: Despite medical awareness, intractable pain is a serious problem in cancer and occurs in up to 2% of advanced cancer patients. However, few data are available concerning the optimal treatment of such patients. The emergence of intractable pain may notably be due to the activation of N-methyl-D-aspartate (NMDA) receptors located in the central nervous system. NMDA antagonists might thus be an interesting approach in such pain syndromes.