• Citer

Synthesis and pharmacological evaluation of some N-arylsulfonyl-N-methyl-N'-(2,2-dimethyl-2H-1-benzopyran-4-yl)ureas structurally related to cromakalim.

par Khelili, Smail;Lebrun, Philippe ;de Tullio, Pascal;Pirotte, Bernard
Référence Bioorganic & medicinal chemistry, 14, 10, page (3530-3534)
Publication Publié, 2006-05

Article révisé par les pairs

• Accès en ligne
• Détails
• Contenu
• Statistiques

Titre:	Synthesis and pharmacological evaluation of some N-arylsulfonyl-N-methyl-N'-(2,2-dimethyl-2H-1-benzopyran-4-yl)ureas structurally related to cromakalim.
Auteur:	Khelili, Smail; Lebrun, Philippe; de Tullio, Pascal; Pirotte, Bernard
Informations sur la publication:	Bioorganic & medicinal chemistry, 14, 10, page (3530-3534)
Statut de publication:	Publié, 2006-05
Sujet CREF:	Sciences bio-médicales et agricoles
Mots-clés:	Contractile activity
	Cromakalim derivatives
	Insulin secretion
	Potassium channel openers
MeSH keywords:	Animals
	Aorta -- drug effects
	Benzopyrans -- chemistry
	Benzopyrans -- pharmacology
	Cromakalim -- analogs & derivatives
	Cromakalim -- chemistry
	Cromakalim -- pharmacology
	Drug Evaluation, Preclinical
	Female
	Hypoglycemic Agents -- pharmacology
	Insulin -- biosynthesis
	Islets of Langerhans -- drug effects
	Molecular Structure
	Rats
	Structure-Activity Relationship
	Urea -- analogs & derivatives
	Urea -- chemistry
	Urea -- pharmacology
	Uterine Contraction -- drug effects
	Vasodilation -- drug effects
	Vasodilator Agents -- chemistry
	Vasodilator Agents -- pharmacology
Note générale:	In Vitro
	Journal Article
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:0968-0896
	info:doi/10.1016/j.bmc.2006.01.009
	info:pii/S0968-0896(06)00044-7
	info:scp/33646488916
	info:pmid/16455262