par Van Cauter, Eve ;Sturis, J;Byrne, M M;Blackman, J D;Scherberg, Neal ;Leproult, Rachel ;Refetoff, Samuel ;Van Reeth, Olivier
Référence Journal of biological rhythms, 8 Suppl, page (S99-108)
Publication Publié, 1993
Référence Journal of biological rhythms, 8 Suppl, page (S99-108)
Publication Publié, 1993
Article révisé par les pairs
Résumé : | The aim of the present research was to determine the magnitude and direction of immediate phase shifts of human rhythms following a single exposure to a 3-hr pulse of bright light or physical activity. The pulse of light or activity was presented under "constant-routine" conditions, and measurements of the resultant phase shifts were performed under the same constant-routine conditions on the first day following pulse presentation. Four overt rhythms that are strongly dependent on circadian timing--namely, the rhythms of plasma cortisol, plasma thyroid-stimulating hormone (TSH), plasma melatonin, and body temperature--were monitored. The analysis of the TSH profiles indicated that exposure to light at about the time of the minimum of body temperature resulted in phase advances averaging less than 1 hr in magnitude. Exposure to light approximately 3 hr before the time of the minimum of body temperature resulted in phase delays of 1-2 hr. Preliminary analyses of the melatonin profiles have confirmed these observations. Our findings regarding the effects of exercise are still inconclusive. |