par Vassart, Gilbert ;Lecocq, Raymond ;Brocas, Huguette;Dumont, Jacques
Référence Biochimica et biophysica acta, 353, 2, page (261-265)
Publication Publié, 1974-06
Article révisé par les pairs
Résumé : Poly(A)-rich RNA extracted from membrane-bound thyroid polysomes has been shown to contain two fractions showing thyroglobulin messenger activity: a heavy 33 S fraction and a 16-18 S fraction. When injected into Xenopus oocyte, the 33 S mRNA specifically promoted the synthesis of a polypeptide chain of about 185 000 daltons as revealed by electrophoresis in sodium dodecylsulphate-polyacrylamide gel after reduction and alkylation. Our results strongly support models of thyroglobulin structure involving the existence of heavy thyroglobulin subunits. © 1974.

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