Titre:
  • The Na+/K+-ATPase is the Achilles heel of multi-drug-resistant cancer cells.
Auteur:Mijatovic, Tatjana; Jungwirth, Ute; Heffeter, Petra; Hoda, Mir Ali Reza; Dornetshuber, Rita; Kiss, Robert; Berger, Walter
Informations sur la publication:Cancer letters, 282, 1, page (30-34)
Statut de publication:Publié, 2009-09
Sujet CREF:Sciences bio-médicales et agricoles
Mots-clés:19-hydroxy-2″oxovoruscharin
Cardenolide
Multi-drug resistance (MDR)
Na+/K+-ATPase targeting
MeSH keywords:Breast Neoplasms
Carcinoma, Non-Small-Cell Lung -- pathology
Carcinoma, Small Cell -- pathology
Carcinoma, Squamous Cell
Cardenolides -- pharmacology
Cell Line, Tumor -- drug effects
Cell Survival -- drug effects
Drug Resistance, Multiple -- physiology
Hela Cells -- drug effects
Humans
Hydroxyurea -- pharmacology
Ligands
Neoplasms -- drug therapy
P-Glycoprotein -- metabolism
Sodium-Potassium-Exchanging ATPase -- drug effects
Sodium-Potassium-Exchanging ATPase -- metabolism
Thiazoles -- pharmacology
Note générale:Journal Article
Langue:Anglais
Identificateurs:urn:issn:0304-3835
info:doi/10.1016/j.canlet.2009.02.048
info:pii/S0304-3835(09)00161-X
info:scp/67649422335
info:pmid/19339106