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Hyperactivated NF-{kappa}B and AP-1 transcription factors promote highly accessible chromatin and constitutive transcription across the interleukin-6 gene promoter in metastatic breast cancer cells.

par Ndlovu, Matladi N. ;Van Lint, Carine ;Van Wesemael, Karlien;Callebert, Pieter;Chalbos, Dany;Haegeman, Guy;Vanden Berghe, Wim
Référence Molecular and cellular biology, 29, 20, page (5488-5504)
Publication Publié, 2009

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Titre:	Hyperactivated NF-{kappa}B and AP-1 transcription factors promote highly accessible chromatin and constitutive transcription across the interleukin-6 gene promoter in metastatic breast cancer cells.
Auteur:	Ndlovu, Matladi N.; Van Lint, Carine; Van Wesemael, Karlien; Callebert, Pieter; Chalbos, Dany; Haegeman, Guy; Vanden Berghe, Wim
Informations sur la publication:	Molecular and cellular biology, 29, 20, page (5488-5504)
Statut de publication:	Publié, 2009
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Breast Neoplasms -- genetics
	Breast Neoplasms -- pathology
	Cell Line, Tumor
	Chromatin -- metabolism
	Ergosterol -- analogs & derivatives
	Ergosterol -- pharmacology
	Gene Expression Regulation, Neoplastic -- drug effects
	Histones -- metabolism
	Humans
	Interleukin-6 -- genetics
	Neoplasm Metastasis
	Promoter Regions, Genetic -- physiology
	Proto-Oncogene Proteins c-fos -- antagonists & inhibitors
	Proto-Oncogene Proteins c-fos -- metabolism
	Proto-Oncogene Proteins c-jun -- metabolism
	RNA, Small Interfering -- metabolism
	Transcription Factor AP-1 -- antagonists & inhibitors
	Transcription Factor AP-1 -- metabolism
	Transcription Factor RelA -- antagonists & inhibitors
	Transcription Factor RelA -- metabolism
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
	SCOPUS: ar.j
Langue:	Anglais
Identificateurs:	urn:issn:0270-7306
	info:doi/10.1128/MCB.01657-08
	info:pii/MCB.01657-08
	info:scp/70350464482
	info:pmid/19687301