• Citer

Alzheimer's disease-like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits.

par Schindowski, Katharina;Bretteville, Alexis;Leroy, Karelle ;Bégard, Séverine;Brion, Jean Pierre ;Hamdane, Malika ;Buée, Luc
Référence The American journal of pathology, 169, 2, page (599-616)
Publication Publié, 2006-08

Article révisé par les pairs

• Accès en ligne
• Détails
• Contenu
• Statistiques

Titre:	Alzheimer's disease-like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits.
Auteur:	Schindowski, Katharina; Bretteville, Alexis; Leroy, Karelle; Bégard, Séverine; Brion, Jean Pierre; Hamdane, Malika; Buée, Luc
Informations sur la publication:	The American journal of pathology, 169, 2, page (599-616)
Statut de publication:	Publié, 2006-08
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Aging
	Alzheimer Disease -- pathology
	Animals
	Behavior, Animal
	Disease Models, Animal
	Gliosis -- pathology
	Hippocampus -- cytology
	Hippocampus -- pathology
	Hippocampus -- ultrastructure
	Humans
	Memory Disorders -- pathology
	Mice
	Mice, Transgenic
	Motor Skills Disorders -- pathology
	Mutation -- genetics
	Nerve Degeneration
	Neurofibrillary Tangles -- ultrastructure
	Phosphorylation
	Protein Conformation
	Synapses -- pathology
	Synaptic Transmission -- physiology
	tau Proteins -- chemistry
	tau Proteins -- genetics
	tau Proteins -- metabolism
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:0002-9440
	info:doi/10.2353/ajpath.2006.060002
	info:pii/169/2/599
	info:scp/33746652117
	info:pmid/16877359
	PMC1698785