par Lofuta Olenga Vuvu, Pierre Gaylord
;Klass, Malgorzata
;Pauwen, Nathalie;Kipula, Mboko Augustin;Van De Borne, Philippe
;Van Muylem, Alain
;Perez Bogerd, Silvia
;Deboeck, Gaël 
Référence Physiological Reports, 13, 9, page (e70368)
Publication Publié, 2025-05-01






Référence Physiological Reports, 13, 9, page (e70368)
Publication Publié, 2025-05-01
Article révisé par les pairs
Résumé : | Exposure to charcoal biomass (CB) pollutants affects the cardiorespiratory system. We assessed cardiopulmonary responses (CPR) to exercise in charcoal producers (CPs) compared to farmers and evaluated the prevalence of exercise-induced bronchoconstriction (EIB). Forty-five CPs and 36 farmers, healthy males aged 23-39, completed a 15-m Incremental Shuttle Walk and Run Test (15-m ISWRT). Air quality index (AQI) and CO intoxication were measured, CPR was assessed through heart rate (HR), blood pressures (SBP, DBP), and spirometry at rest, peak exercise, and during recovery at 5 and 15 min. Aerobic capacity (VO2 max) was estimated from the distance covered during the 15-m ISWRT, and EIB was defined as a >10% decrease in FEV1 from baseline values. AQI was worse in charcoal workplaces, and CPs had higher CO intoxication than farmers (p < 0.0001). Both groups reached maximal exercise %HRmax: 84 (82-89) versus 84 (80-89), p = 0.37 and showed similar predicted VO2 max 36.2 (31.1-43.1) versus 38.9 (32.2-43.7) mL/kg/min, p = 0.60. However, after ISWRT, CPs had lower FEV1 than farmers (2.9 ± 0.6 vs. 3.3 ± 0.6 L, p < 0.003) and slower recovery. EIB prevalence was higher in CPs (60.0% vs. 27.8%, p = 0.006). Chronic exposure to CB increases EIB in healthy CPs, suggesting heightened airway hyperreactivity. |