par Amenaghawon, Andrew Nosakhare;Ayere, Joshua Efosa;Amune, Ubani Oluwaseun;Otuya, Ifechukwude Christopher;Abuga, Emmanuel Christopher;Anyalewechi, Chinedu Lewis;Okoro, Oseweuba Valentine;Okolie, Jude J.A.;Oyefolu, Peter Kayode;Eshiemogie, Steve Oshiokhai;Osahon, Blessing Esohe;Omede, Melissa;Eshiemogie, Stanley Aimhanesi;Igemhokhai, Shedrach;Okedi, Maxwell Ogaga;Kusuma, Heri Septya;Muojama, Obiora Ebuka;Shavandi, Armin ;Darmokoesoemo, Handoko
Référence Environmental research, 251, 118703
Publication Publié, 2024-09-01
Référence Environmental research, 251, 118703
Publication Publié, 2024-09-01
Article révisé par les pairs
Résumé : | Organic acids are important compounds with numerous applications in different industries. This work presents a comprehensive review of the biological synthesis of oxalic acid, an important organic acid with many industrial applications. Due to its important applications in pharmaceuticals, textiles, metal recovery, and chemical and metallurgical industries, the global demand for oxalic acid has increased. As a result, there is an increasing need to develop more environmentally friendly and economically attractive alternatives to chemical synthesis methods, which has led to an increased focus on microbial fermentation processes. This review discusses the specific strategies for microbial production of oxalic acid, focusing on the benefits of using bio-derived substrates to improve the economics of the process and promote a circular economy in comparison with chemical synthesis. This review provides a comprehensive analysis of the various fermentation methods, fermenting microorganisms, and the biochemistry of oxalic acid production. It also highlights key sustainability challenges and considerations related to oxalic acid biosynthesis, providing important direction for further research. By providing and critically analyzing the most recent information in the literature, this review serves as a comprehensive resource for understanding the biosynthesis of oxalic acid, addressing critical research gaps, and future advances in the field. |