par Courboin, E.;Mathieu, Romain;Panetta, Valentina;Mjaess, Georges;Diamand, Romain ;Verhoest, Grégory;Roumiguié, Mathieu;Bajeot, A.;Soria, Francesco;Lonati, Chiara;Simeone, Claudio;Simone, Giuseppe;Anceschi, Umberto;Umari, Paolo;Sridhar, Ashwin;Kelly, John;Mertens, Laura L.S.;Sanchez-Salas, Rafael;Colomer, Anna;Cerruto, Maria Angela;Antonelli, Alessandro;Krajewski, Wojciech;Quackels, Thierry ;Peltier, Alexandre ;Montorsi, Francesco;Briganti, Alberto;Teoh, Jeremy Yuen Chun;Pradere, Benjamin;Moschini, Marco;Roumeguere, Thierry ;Albisinni, Simone
Référence Cancers (Basel), 15, 19, 4732
Publication Publié, 2023-10
Référence Cancers (Basel), 15, 19, 4732
Publication Publié, 2023-10
Article révisé par les pairs
Résumé : | Background: For non-muscle-invasive bladder cancer (NMIBC) requiring radical surgery, limited data are available comparing robotic-assisted radical cystectomy with intracorporeal urinary diversion (iRARC) to open radical cystectomy (ORC). The objective of this study was to compare the two surgical techniques. Methods: A multicentric cohort of 593 patients with NMIBC undergoing iRARC or ORC between 2015 and 2020 was prospectively gathered. Perioperative and pathologic outcomes were compared. Results: A total of 143 patients operated on via iRARC were matched to 143 ORC patients. Operative time was longer in the iRARC group (p = 0.034). Blood loss was higher in the ORC group (p < 0.001), with a consequent increased post-operative transfusion rate in the ORC group (p = 0.003). Length of stay was longer in the ORC group (p = 0.007). Post-operative complications did not differ significantly (all p > 0.05). DFS at 60 months was 55.9% in ORC and 75.2% in iRARC with a statistically significant difference (p = 0.033) found in the univariate analysis. Conclusion: We found that iRARC for patients with NMIBC is safe, associated with a lower blood loss, a lower transfusion rate and a shorter hospital stay compared to ORC. Complication rates were similar. No significant differences in survival analyses emerged across the two techniques. |