Titre:
  • Homeostatic PD-1 signaling restrains EOMES-dependent oligoclonal expansion of liver-resident CD8 T cells.
Auteur:Le Moine, Marie; Azouz, Abdulkader; Sánchez Sánchez, Guillem; Dejolier, Solange; Nguyen, Muriel; Thomas, Séverine; Shala, Valdrin; Dreidi, Hacène; Denanglaire, Sébastien; Libert, Frédérick; Vermijlen, David; Andris, Fabienne; Goriely, Stanislas
Informations sur la publication:Cell reports, 42, 8, page (112876)
Statut de publication:Publié, 2023-08-01
Sujet CREF:Sciences bio-médicales et agricoles
Immunologie
Mots-clés:CD8 T cells
CP: Immunology
EOMES
T cell exhaustion
immune checkpoint blockade
liver
resident memory
transcription factor
MeSH keywords:Humans
CD8-Positive T-Lymphocytes -- metabolism
Gene Expression Regulation
Liver -- metabolism
Signal Transduction
Receptors, Antigen, T-Cell -- metabolism
T-Box Domain Proteins -- genetics -- metabolism
Langue:Anglais
Identificateurs:urn:issn:2211-1247
info:doi/10.1016/j.celrep.2023.112876
info:pii/S2211-1247(23)00887-2
info:pmid/37543948