par Saxena, Sarah 
;Nuyens, Vincent;Rodts, Christopher ;Jamar, Kristina Edouardovna ;Albert, Adelin;Seidel, Laurence;Cherkaoui-Malki, Mustapha;Boogaerts, Jean G;Wulff, Heike;Maze, Mervyn;Kruys, Véronique ;Vamecq, Joseph
Référence BMC anesthesiology, 23, 1, page (80)
Publication Publié, 2023-03-01
;Nuyens, Vincent;Rodts, Christopher ;Jamar, Kristina Edouardovna ;Albert, Adelin;Seidel, Laurence;Cherkaoui-Malki, Mustapha;Boogaerts, Jean G;Wulff, Heike;Maze, Mervyn;Kruys, Véronique ;Vamecq, JosephRéférence BMC anesthesiology, 23, 1, page (80)
Publication Publié, 2023-03-01
Article révisé par les pairs
| Résumé : | Potassium channels (KCa3.1; Kv1.3; Kir2.1) are necessary for microglial activation, a pivotal requirement for the development of Perioperative Neurocognitive Disorders (PNDs). We previously reported on the role of microglial Kv1.3 for PNDs; the present study sought to determine whether inhibiting KCa3.1 channel activity affects neuroinflammation and prevents development of PND. |
