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Loss of tetraspanin-7 expression reduces pancreatic β-cell exocytosis Ca2+ sensitivity but has limited effect on systemic metabolism.

par McLaughlin, Kerry;Acreman, Samuel;Nawaz, Sameena;Cutteridge, Joseph;Clark, Anne;Knudsen, Jakob G;Denwood, Geoffrey;Spigelman, Aliya AF;Manning Fox, Jocelyn JE;Singh, Sumeet Pal ;MacDonald, Patrick E;Hastoy, Benoit;Zhang, Quan
Référence Diabetic medicine, 39, 12, page (e14984)
Publication Publié, 2022-12-01

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Titre:	Loss of tetraspanin-7 expression reduces pancreatic β-cell exocytosis Ca2+ sensitivity but has limited effect on systemic metabolism.
Auteur:	McLaughlin, Kerry; Acreman, Samuel; Nawaz, Sameena; Cutteridge, Joseph; Clark, Anne; Knudsen, Jakob G; Denwood, Geoffrey; Spigelman, Aliya AF; Manning Fox, Jocelyn JE; Singh, Sumeet Pal; MacDonald, Patrick E; Hastoy, Benoit; Zhang, Quan
Informations sur la publication:	Diabetic medicine, 39, 12, page (e14984)
Statut de publication:	Publié, 2022-12-01
Sujet CREF:	Sciences bio-médicales et agricoles
Mots-clés:	exocytosis
	insulin
	synaptotagmin
	tetraspanin-7
	β-cell
MeSH keywords:	Animals
	Humans
	Mice
	Exocytosis -- physiology
	Glucose -- metabolism
	Insulin -- metabolism
	Insulin-Secreting Cells -- metabolism
	Islets of Langerhans -- metabolism
	Tetraspanins -- genetics -- metabolism
Langue:	Anglais
Identificateurs:	urn:issn:0742-3071
	info:doi/10.1111/dme.14984
	info:pmid/36264270
	PMC9828109