par Schroder, Elisa ;Campanella, Salvatore
Référence Neuroscience of Alcohol: Mechanisms and Treatment, Elsevier, page (187-194)
Publication Publié, 2019-01
Partie d'ouvrage collectif
Résumé : Response inhibition is a key component regarding substance use as it allows subjects to stop drug-seeking and drug-consummation behaviors and is often specifically altered in addiction. If the specific alteration of response inhibition in addiction has been extensively studied, little has been developed regarding the neural correlates of response inhibition in alcohol users. This chapter provides an overview of neural correlates of response inhibition and the specific impact of alcohol consumption thanks to Go/No-Go tasks. Results suggest the link between alcohol use and response inhibition is twofold: (1) Adolescents who will later show patterns of heavy drinking display vulnerabilities indexed by a hypoactivation of brain areas linked to response inhibition; and (2) young heavy drinkers tend to display a general hyperactivation of these brain areas, suggesting the achievement of the task requires more cognitive efforts than for controls, even with small doses of alcohol.