par Rocha-Ferreira, Eridan;Kelen, Dorottya
;Faulkner, Stuart;Broad, Kevin D;Chandrasekaran, Manigandan;Kerenyi, Áron;Kato, Takenori;Bainbridge, Alan;Golay, Xavier;Sullivan, Mark;Kramer, Boris W;Robertson, Nicola NJ
Référence Journal of neuroinflammation, 14, 1, page (44)
Publication Publié, 2017

Référence Journal of neuroinflammation, 14, 1, page (44)
Publication Publié, 2017
Article révisé par les pairs
Résumé : | Inflammatory cytokines are implicated in the pathogenesis of perinatal hypoxia-ischemia (HI). The influence of hypothermia (HT) on cytokines after HI is unclear. Our aim was to assess in a piglet asphyxia model, under normothermic (NT) and HT conditions: (i) the evolution of serum cytokines over 48 h and (ii) cerebrospinal fluid (CSF) cytokine levels at 48 h; (iii) serum pro/anti-inflammatory cytokine profile over 48 h and (iv) relation between brain injury measured by magnetic resonance spectroscopy (MRS) and brain TUNEL positive cells with serum cytokines, serum pro/anti-inflammatory cytokines and CSF cytokines. |