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Management of young women with early breast cancer

par Poggio, Francesca;Lambertini, Matteo ;Bighin, Claudia;Conte, Benedetta;Blondeaux, Eva;D'Alonzo, Alessia;Dellepiane, Chiara;Boccardo, Francesco;Del Mastro, Lucia
Référence ESMO Open, 3, e000458
Publication Publié, 2018-11

Article révisé par les pairs

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Résumé :

Breast cancer is still the most frequent cancer diagnosed in women aged ≤40 years and the primary cause of death in this age group. The management of these patients needs a dedicated approach involving a multidisciplinary team that takes into account their treatment and survivorship issues. The present review aims to provide a perspective on the many challenges associated with treatment of young women with early breast cancer. We will focus on the standard (neo)adjuvant treatment, highlighting the paucity of age-specific results about the available genomic signatures, the groundbreaking landscape of adjuvant endocrine therapy and the relevant issue of the fertility preservation.