Article révisé par les pairs
Titre:
  • A CARD9 Founder Mutation Disrupts NF-κB Signaling by Inhibiting BCL10 and MALT1 Recruitment and Signalosome Formation
Auteur:De Bruyne, Marieke; Hoste, Levi; Bogaert, Delfien D.J.; Van den Bossche, Lien; Tavernier, Simon S.J.; Parthoens, Eef; Migaud, Mélanie; Konopnicki, Deborah; Yombi, Jean-Cyr; Lambrecht, Bart; Van Daele, Sabine; Alves de Medeiros, Ana Karina; Brochez, Lieve; Beyaert, Rudi; De Baere, Elfride; Puel, Anne; Casanova, Jean-Laurent; Goffard, Jean-Christophe; Savvides, Savvas S.N.; Haerynck, Filomeen; Staal, Jens; Dullaers, Melissa
Informations sur la publication:Frontiers in immunology, 9, page (2366)
Statut de publication:Publié, 2018
Sujet CREF:Généralités
Mots-clés:BCL10
CARD9 deficiency
CBM complex
filament
founder mutation
MALT1
NF-κB
signalosome
MeSH keywords:B-Cell CLL-Lymphoma 10 Protein -- metabolism
CARD Signaling Adaptor Proteins -- chemistry -- genetics
Cell Line
Disease Susceptibility
Female
Founder Effect
Gain of Function Mutation
Humans
Male
Models, Molecular
Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein -- metabolism
Mutation
NF-kappa B -- metabolism
Pedigree
Protein Binding
Protein Conformation
Signal Transduction
Structure-Activity Relationship
T-Lymphocyte Subsets -- immunology -- metabolism
Note générale:SCOPUS: ar.j
Langue:Anglais
Identificateurs:urn:issn:1664-3224
info:doi/10.3389/fimmu.2018.02366
info:scp/85056650522
info:pmid/30429846
PMC6220056

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