Article révisé par les pairs
Titre:
  • Pancreatic β-cell tRNA hypomethylation and fragmentation link TRMT10A deficiency with diabetes.
Auteur:Cosentino, Cristina; Toivonen, Sanna; Diaz Villamil, Esteban; Atta, Mohamed MA; Ravanat, Jean-Luc; Demine, Stéphane; Schiavo, Andréa Alex; Pachera, Nathalie; Deglasse, Jean-Philippe; Jonas, Jean-Christophe JJC; Balboa, Diego; Otonkoski, Timo; Pearson, Ewan ER; Marchetti, Piero; Eizirik, Decio L.; Cnop, Miriam; Igoillo Esteve, Mariana
Informations sur la publication:Nucleic acids research, 46, 19, page (10302-10318)
Statut de publication:Publié, 2018-11-02
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Aged
Animals
Apoptosis -- genetics
Cell Death -- genetics
Cell Differentiation -- genetics
Cells, Cultured
DNA Fragmentation
DNA Methylation
Diabetes Mellitus -- genetics -- metabolism
Genetic Linkage
Humans
Induced Pluripotent Stem Cells -- physiology
Insulin-Secreting Cells -- metabolism -- physiology
Methyltransferases -- deficiency -- genetics -- metabolism
Middle Aged
Mutation
RNA, Transfer -- metabolism
Rats
Note générale:SCOPUS: ar.j
Miriam Cnop and Mariana Igoillo Esteve share corresponding authorship
Langue:Anglais
Identificateurs:urn:issn:0305-1048
info:doi/10.1093/nar/gky839
info:pii/5104737
info:scp/85056260611
info:pmid/30247717
PMC6212784

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