Article révisé par les pairs
| Résumé : | Erythrocyte destruction in hemolytic anemia associated with cancer is essentially an extraerythrocytic anomaly of the plasma or the vascular lumen. While the mechanism of the destruction of the red blood corpuscles is more or less elucidated, the nature of the association of cancer and hemolytic anemia by autoantibodies on the other hand remains obscure. Hemolytic anemia by autoantibodies occurs very often in patients with depressed immunity. Moreover, immunity deficits have been demonstrated in malignant lymphomas and cancer in general. The result is that in certain cases the depression of immunity common to both diseases could be one of the causes, which explains their frequent association. Finally, it cannot be excluded that in certain cases the tumor may be responsible for the antibody production. |
