par Maurus, Renée ;Otten, Jacques
Référence Recent Results in Cancer Research, NO.67, page (78-84)
Publication Publié, 1979
Article révisé par les pairs
Résumé : The great amount of information gathered over 20 years on the biochemistry of neuroblastoma has provided the clinician with reliable methods of diagnosis. They also enable him to trace clinically silent tumor cell populations and to detect incipient recurrence. Whether this last possibility has really improved ultimate control of the disease is not clearly established. The methods used in many hospital laboratories for the evaluation of catecholamine metabolism lag far behind those developed in some research centers. It is possible that only marginal benefit is derived from the biochemical follow-up of the patients when it is restricted to the measurement of VMA excretion with rather unspecific methods. The usefulness of a frequent and detailed analysis of catecholamine metabolism in each patient remains to be evaluated.