par Ichai, Carole;Preiser, Jean-Charles 
Référence Metabolic Disorders and Critically Ill Patients: From Pathophysiology to Treatment, Springer International Publishing, page (379-397)
Publication Publié, 2017-01
Référence Metabolic Disorders and Critically Ill Patients: From Pathophysiology to Treatment, Springer International Publishing, page (379-397)
Publication Publié, 2017-01
Partie d'ouvrage collectif
| Résumé : | Stress hyperglycemia refers usually to a transient elevation of blood glucose level (BGL) which occurs during acute diseases in patients without previous evidence of diabetes. This metabolic disorder is frequent and can reach up to 50% of critically ill patients [1, 2]. Many data support the relationship between stress hyperglycemia and an increased morbidity and mortality. A great enthusiasm has been triggered in 2001 after the first clinical trial showing that a tight glycemic control (TGC) in intensive care unit (ICU) reduced significantly the mortality rate and improved several other outcome variables in critically ill patients [3]. However, further studies failed to confirm these results leading to question about the real benefit and external validity of a TGC in ICU [4-8]. The recent discussions and controversies revealed the complexity of the metabolic response to stress. |
