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TYK2, a Candidate Gene for Type 1 Diabetes, Modulates Apoptosis and the Innate Immune Response in Human Pancreatic bêta-Cells.

par Marroquí, Laura ;Dos Santos, Reinaldo Sousa;Fløyel, Tina;Grieco, Fabio Arturo ;Santin Gomez, Izortze ;Op De Beeck, Anne ;Marselli, Lorella;Marchetti, Piero;Pociot, Flemming Michael;Eizirik, Decio L.
Référence Diabetes (New York, N.Y.), 64, 11, page (3808-3817)
Publication Publié, 2015-11

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Titre:	TYK2, a Candidate Gene for Type 1 Diabetes, Modulates Apoptosis and the Innate Immune Response in Human Pancreatic bêta-Cells.
Auteur:	Marroquí, Laura; Dos Santos, Reinaldo Sousa; Fløyel, Tina; Grieco, Fabio Arturo; Santin Gomez, Izortze; Op De Beeck, Anne; Marselli, Lorella; Marchetti, Piero; Pociot, Flemming Michael; Eizirik, Decio L.
Informations sur la publication:	Diabetes (New York, N.Y.), 64, 11, page (3808-3817)
Statut de publication:	Publié, 2015-11
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Apoptosis -- genetics -- immunology
	Cell Line
	Cell Survival -- genetics
	Chemokine CXCL10 -- genetics -- metabolism
	Diabetes Mellitus, Type 1 -- genetics -- metabolism
	Genes, MHC Class I -- physiology
	Genome-Wide Association Study
	Humans
	Immunity, Innate -- genetics
	Insulin-Secreting Cells -- immunology -- metabolism
	Interferon-alpha -- genetics -- metabolism
	Phosphorylation
	Polymorphism, Single Nucleotide
	TYK2 Kinase -- genetics -- metabolism
Langue:	Anglais
Identificateurs:	urn:issn:0012-1797
	info:doi/10.2337/db15-0362
	info:pii/db15-0362
	info:pmid/26239055