par Frost, Hannah R C H.;Laho, Delphine 
;Sanderson-Smith, Martina L;Licciardi, Paul;Donath, Susan;Curtis, Nigel;Kado, Joseph;Dale, James B;Steer, Andrew C;Smeesters, Pierre
Référence Clinical infectious diseases, 65, 9, page (1523-1531)
Publication Publié, 2017-10
;Sanderson-Smith, Martina L;Licciardi, Paul;Donath, Susan;Curtis, Nigel;Kado, Joseph;Dale, James B;Steer, Andrew C;Smeesters, Pierre Référence Clinical infectious diseases, 65, 9, page (1523-1531)
Publication Publié, 2017-10
Article révisé par les pairs
| Résumé : | Group A Streptococcus (GAS) skin infections are particularly prevalent in developing nations. The GAS M protein, by which strains are differentiated into >220 different emm types, is immunogenic and elicits protective antibodies. A major obstacle for vaccine development has been the traditional understanding that immunity following infection is restricted to a single emm type. However, recent evidence has led to the hypothesis of immune cross-reactivity between emm types. |
