par Michel, Thomas;Vanderwinden, Jean-Marie 
;Vanderhaeghen, Jean-Jacques ;De Laet, Marc-Henri
Référence The New England journal of medicine, 327, 23, page (1690-1691)
Publication Publié, 1992-12
;Vanderhaeghen, Jean-Jacques ;De Laet, Marc-Henri Référence The New England journal of medicine, 327, 23, page (1690-1691)
Publication Publié, 1992-12
Lettre à l'éditeur
| Résumé : | To the Editor: Vanderwinden et al. (Aug. 20 issue)1 ascribe infantile hypertrophic pyloric stenosis to a deficiency of nitric oxide synthase in enteric nerve fibers. Although this is an attractive hypothesis, it is poorly supported by the results presented. Using a histochemical method to identify NADPH diaphorase, which is known to be a fairly specific marker for nitric oxide synthase activity in both brain2 and endothelial3 cells, the authors found reduced activity in enteric nerve fibers in pyloromyotomy specimens obtained from infants with pyloric stenosis. Enteric nervous system tissues were identified with the use of tau antiserum; these same tissues… © 1992, Massachusetts Medical Society. All rights reserved. |
