• Citer

Inhibition of hIAPP Amyloid Aggregation and Pancreatic Beta-Cell Toxicity by OH-Terminated PAMAM Dendrimer.

par Gurzov, Esteban Nicolas ;Wang, Bo;Pilkington, Emily H;Chen, Pengyu;Kakinen, Aleksandr;Stanley, William J;Litwak, Sara A;Hanssen, Eric G;Davis, Thomas P;Ding, Feng;Ke, Pu Chun
Référence Small, 12, 12, page (1615-1626)
Publication Publié, 2016-03

Article révisé par les pairs

• Détails
• Contenu

Titre:	Inhibition of hIAPP Amyloid Aggregation and Pancreatic Beta-Cell Toxicity by OH-Terminated PAMAM Dendrimer.
Auteur:	Gurzov, Esteban Nicolas; Wang, Bo; Pilkington, Emily H; Chen, Pengyu; Kakinen, Aleksandr; Stanley, William J; Litwak, Sara A; Hanssen, Eric G; Davis, Thomas P; Ding, Feng; Ke, Pu Chun
Informations sur la publication:	Small, 12, 12, page (1615-1626)
Statut de publication:	Publié, 2016-03
Sujet CREF:	Sciences bio-médicales et agricoles
Mots-clés:	amyloid fibrillation
	cytotoxicity
	discrete molecular dynamics simulations
	high-throughput dynamic light scattering
	human islet amyloid polypeptide
	hydroxyl-terminated polyamidoamine dendrimer
	protein aggregation
MeSH keywords:	Amyloid -- metabolism
	Cell Death -- drug effects
	Cytoprotection -- drug effects
	Dendrimers -- toxicity
	Humans
	Hydroxylation
	Insulin-Secreting Cells -- drug effects -- pathology
	Islet Amyloid Polypeptide -- metabolism
	Models, Molecular
	Protein Aggregates -- drug effects
	Protein Multimerization -- drug effects
	Thiazoles -- metabolism
Langue:	Anglais
Identificateurs:	urn:issn:1613-6810
	info:doi/10.1002/smll.201502317
	info:pmid/26808649