• Citer

The combined effects of extracorporeal membrane oxygenation and renal replacement therapy on meropenem pharmacokinetics: a matched cohort study

par Shekar, Kiran;Fraser, John J.F.;Taccone, Fabio ;Welch, Susan;Wallis, Steven S.C.;Mullany, Daniel Vincent;Lipman, Jeffrey;Roberts, Jason A
Référence Critical care, 18, 6, page (565)
Publication Publié, 2014-12

Article révisé par les pairs

• Accès en ligne
• Détails
• Contenu
• Statistiques

Résumé :

INTRODUCTION: The scope of extracorporeal membrane oxygenation (ECMO) is expanding; however, optimal drug prescription during ECMO remains a developing science. Currently, there are no clear guidelines for antibiotic dosing during ECMO. This open-label, descriptive, matched-cohort pharmacokinetics (PK) study aimed to compare the PK of meropenem in ECMO patients to critically ill patients with sepsis not receiving ECMO (controls).