Pyoderma gangrenosum with altered cellular immunity and dermonecrotic factor

Delescluse, Jacques; De Bast, Claude; Achten, Georges

doi:doi/10.1111/j.1365-2133.1972.tb07441.x

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Pyoderma gangrenosum with altered cellular immunity and dermonecrotic factor

par Delescluse, Jacques

;De Bast, Claude

;Achten, Georges

Référence British journal of dermatology, 87, 6, page (529-532)
Publication Publié, 1972

Article révisé par les pairs

Résumé :

Summary.— A patient with severe pyoderma gangrenosum, without any other associated conditions, is reported. She was found to present 2 major abnormalities of cellular immunity, i.e. lack of lymphocyte cytotoxicity induced by phytohaemagglutinin and failure of dinitrofluorobenzene sensitization. Intra dermal reactions to tuberculin, trichophytin and candidin were negative, while intradermal injections of streptoccal antigen twice provoked large ulcers at the sites of injection. Dermonecrotic factor was present in her serum. High doses of steroids had to be given to heal her ulcers. Copyright © 1972, Wiley Blackwell. All rights reserved

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